DOWN X DOWN › week 16 › 49ers at Colts
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Week 16 · Monday 8:15 PM ET · Lucas Oil Stadium

SFvsIND

49ers offensevsColts defense

Season numbers through Week 22: 19 games for 49ers, 17 for Colts. Ranks are out of 32; #1 is the best offense or the stingiest defense.

How it played out · win probability, snap by snapFinal · SF 48 · IND 27

The 49ers won 48–27 and were favored the whole way, never below 52%. The biggest single swing came at Q2 14:19, 13 points for the Colts.

At kickoffSF 69%SF by 4.5 on the line
SF low point52%Q1 10:31 · down 6⁠–⁠0
Swings past 50%0times the favorite changed
Biggest swing13 ptsIND · Q2 14:19
IND wins50%SF wins
Q1Q2Q3Q4

The plays that swung it

  1. 1Q2 14:19INDP.Rivers pass deep middle to A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-D.Luter, Defensive Pass Interference, declined.20% → 33%+13
  2. 2Q1 7:14SFE.Pineiro kicks 56 yards from SF 35 to IND 9. A.Abdullah to IND 27 for 18 yards (J.Brown). FUMBLES (J.Brown), RECOVERED by SF-J.Tonges at IND 26.66% → 77%+11
  3. 3Q1 11:45INDP.Rivers pass short right to J.Downs to SF 23 for 13 yards (U.Stout).33% → 42%+9
  4. 4Q2 9:42SFB.Purdy pass short right to G.Kittle for 11 yards, TOUCHDOWN.75% → 83%+8
  5. 5Q1 14:14INDP.Rivers pass short middle to J.Taylor to IND 49 for 19 yards (M.Mustapha).28% → 36%+8

Win probability is nflverse's model, which starts from the betting line and updates before every snap with the score, the clock, down, distance, field position and timeouts. A swing is the change in one team's chance across a play, in percentage points. The turning point is the play after which the winner never fell to 50% again.

Box score · every offensive player who touched the ballWeek 16

B.Purdy led the 49ers at +22.7 EPA (25 of 34 for 295). A.Pierce led the Colts at +9.6 EPA (4 catches for 86).

SF 49ers

PassingC/AYdsTDINTSkEPA
B.Purdy95%25/34295511+20.5
RushingCarShareYdsTDEPA
C.McCaffrey80%2168%117+2.9
B.Robinson15%516%20-0.3
M.Jones5%310%-3-3.0
B.Purdy95%26%11+2.2
ReceivingTgtShareRecYdsTDEPA
C.McCaffrey80%824%6292+3.2
G.Kittle62%824%71151+9.8
J.Jennings82%618%5711+9.1
K.Bourne70%515%327-4.3
D.Robinson44%26%2231+2.2
J.Tonges24%26%17+0.6
B.Robinson15%13%00-0.6
S.Moore11%13%123+2.0

Defense D.Winters 1 INT, C.West 1 sack, A.Collins 1 sack · Kicking E.Pineiro 2/3 FG (long 38)

IND Colts

PassingC/AYdsTDINTSkEPA
P.Rivers93%23/35277212+2.9
R.Leonard7%0/10-3.3
RushingCarShareYdsTDEPA
J.Taylor88%1680%461-0.4
T.Goodson8%315%9-1.2
J.Downs78%15%3-0.2
ReceivingTgtShareRecYdsTDEPA
J.Downs78%925%565+3.3
T.Warren88%925%330-11.8
M.Pittman93%514%432+0.2
A.Pierce97%411%4862+9.6
J.Taylor88%38%333+3.1
M.Alie-Cox22%26%216+1.4
A.Ogletree8%26%111+0.5
A.Abdullah7%13%14+0.9
C.Owen2%13%00-3.3

Defense C.Bynum 1 INT, L.Latu 1 sack · Kicking B.Grupe 2/2 FG (long 51)

Each player's line for this game from nflverse's weekly stats; the percentage beside his name is his share of the offense's snaps. Share is his part of the team's carries or targets in this game. Defense lists sacks and interceptions; kicking lists field goals.

Keys to the game · from the season numbers, not this game alone4 reads
01
Biggest edge

Third downs favor 49ers

49ers convert 51% of third downs (1st). Colts allow 44% (25th).

02
Opportunity

Deep left is open

Colts are worst against deep left throws, allowing +0.86 EPA per attempt. 49ers send 8% of their throws there. That is a small part of their offense so far.

03
Watch out

Ground game stalls

49ers average 3.7 yards per carry (29th). Colts allow 3.8 (5th).

04
Wash

Yards per play

Call this one even. 49ers gain 5.6 yards per play (11th). Colts give up 5.4 (17th), with the league at 5.4.

The series · 49ers and Colts since 1999, and this season's records7 meetings

The Colts lead the series 5–2 since 1999 (they first met in 2001). This game is the latest meeting.

49ers at home0–3the 49ers' record
In Indianapolis2–2the 49ers' record
Most points49ers 48 · Colts 302025 · 2021
Biggest win49ers by 21 · Colts by 252025 · 2005

The last 5

2025 · Wk 16SF 48 at IND 27
2021 · Wk 7IND 30 at SF 18
2017 · Wk 5 · OTSF 23 at IND 26
2013 · Wk 3IND 27 at SF 7
2009 · Wk 8SF 14 at IND 18

2025 records

49ersColts
Overall12–58–9
Division4–22–4
Conference9–36–6
Other conference3–22–3
Home5–36–3
Away7–22–6
Last 5WWWWLLLLLL
StreakLost 1Lost 7
Points a game25.7 – 21.827.4 – 24.2

Every meeting since 1999, regular season and playoffs, from nflverse's game list, which starts in 1999; the all-time series goes back further. Franchises that moved count as one team (the Raiders, Chargers and Rams). Home and away are from the 49ers' side. Records are this regular season.

Head to head · SF offense against IND defense
StatSF SF offFavors SF · Favors INDIND IND def allowsNFL avg
Overall
EPA per play
+0.06#9
+0.00#16+0.01
Success rate
48%#3
45%#2344%
Yards per play
5.6#11
5.4#175.4
Explosive play rate
9%#22
9%#1410%
Passing
Pass EPA per dropback
+0.13#8
+0.04#18+0.01
Sack rate
5%#4
6%#257%
Running
Run EPA per carry
-0.04#13
-0.09#8-0.05
Yards per carry
3.7#29
3.8#54.3
Money downs
3rd down conversion
51%#1
44%#2540%
Red zone TD rate
69%#2
56%#1259%
Targets by position
WR yards per game
124#24
168#31140
TE yards per game
57#12
70#3153
TE targets per game
7.6#13
8.4#297.3
RB receiving yards per game
69#1
24#432
Where the ball goes · EPA per throwDeep is 15+ air yds

49ers: EPA per throw

Left
Middle
Right
Deep
+0.178% of throws
+0.765% of throws
+0.554% of throws
Short
+0.2333% of throws
+0.2321% of throws
+0.1130% of throws

Colts: EPA allowed per throw

Left
Middle
Right
Deep
+0.8642 throws
+0.2720 throws
+0.0858 throws
Short
+0.05172 throws
+0.29110 throws
+0.01220 throws

Green gains more than expected, red loses value. Cells with fewer than 5 throws are grayed out.