DOWN X DOWN › week 16 › 49ers at Colts
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Week 16 · Monday 8:15 PM ET · Lucas Oil Stadium

INDvsSF

Colts offensevs49ers defense

Season numbers through Week 22: 17 games for Colts, 19 for 49ers. Ranks are out of 32; #1 is the best offense or the stingiest defense.

How it played out · win probability, snap by snapFinal · SF 48 · IND 27

The 49ers won 48–27 and were favored the whole way, never below 52%. The biggest single swing came at Q2 14:19, 13 points for the Colts.

At kickoffSF 69%SF by 4.5 on the line
SF low point52%Q1 10:31 · down 6⁠–⁠0
Swings past 50%0times the favorite changed
Biggest swing13 ptsIND · Q2 14:19
IND wins50%SF wins
Q1Q2Q3Q4

The plays that swung it

  1. 1Q2 14:19INDP.Rivers pass deep middle to A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-D.Luter, Defensive Pass Interference, declined.20% → 33%+13
  2. 2Q1 7:14SFE.Pineiro kicks 56 yards from SF 35 to IND 9. A.Abdullah to IND 27 for 18 yards (J.Brown). FUMBLES (J.Brown), RECOVERED by SF-J.Tonges at IND 26.66% → 77%+11
  3. 3Q1 11:45INDP.Rivers pass short right to J.Downs to SF 23 for 13 yards (U.Stout).33% → 42%+9
  4. 4Q2 9:42SFB.Purdy pass short right to G.Kittle for 11 yards, TOUCHDOWN.75% → 83%+8
  5. 5Q1 14:14INDP.Rivers pass short middle to J.Taylor to IND 49 for 19 yards (M.Mustapha).28% → 36%+8

Win probability is nflverse's model, which starts from the betting line and updates before every snap with the score, the clock, down, distance, field position and timeouts. A swing is the change in one team's chance across a play, in percentage points. The turning point is the play after which the winner never fell to 50% again.

Box score · every offensive player who touched the ballWeek 16

B.Purdy led the 49ers at +22.7 EPA (25 of 34 for 295). A.Pierce led the Colts at +9.6 EPA (4 catches for 86).

SF 49ers

PassingC/AYdsTDINTSkEPA
B.Purdy95%25/34295511+20.5
RushingCarShareYdsTDEPA
C.McCaffrey80%2168%117+2.9
B.Robinson15%516%20-0.3
M.Jones5%310%-3-3.0
B.Purdy95%26%11+2.2
ReceivingTgtShareRecYdsTDEPA
C.McCaffrey80%824%6292+3.2
G.Kittle62%824%71151+9.8
J.Jennings82%618%5711+9.1
K.Bourne70%515%327-4.3
D.Robinson44%26%2231+2.2
J.Tonges24%26%17+0.6
B.Robinson15%13%00-0.6
S.Moore11%13%123+2.0

Defense D.Winters 1 INT, C.West 1 sack, A.Collins 1 sack · Kicking E.Pineiro 2/3 FG (long 38)

IND Colts

PassingC/AYdsTDINTSkEPA
P.Rivers93%23/35277212+2.9
R.Leonard7%0/10-3.3
RushingCarShareYdsTDEPA
J.Taylor88%1680%461-0.4
T.Goodson8%315%9-1.2
J.Downs78%15%3-0.2
ReceivingTgtShareRecYdsTDEPA
J.Downs78%925%565+3.3
T.Warren88%925%330-11.8
M.Pittman93%514%432+0.2
A.Pierce97%411%4862+9.6
J.Taylor88%38%333+3.1
M.Alie-Cox22%26%216+1.4
A.Ogletree8%26%111+0.5
A.Abdullah7%13%14+0.9
C.Owen2%13%00-3.3

Defense C.Bynum 1 INT, L.Latu 1 sack · Kicking B.Grupe 2/2 FG (long 51)

Each player's line for this game from nflverse's weekly stats; the percentage beside his name is his share of the offense's snaps. Share is his part of the team's carries or targets in this game. Defense lists sacks and interceptions; kicking lists field goals.

Keys to the game · from the season numbers, not this game alone4 reads
01
Biggest edge

Clean pockets

Colts take a sack on 5% of dropbacks (7th). 49ers get home on 4% (32nd). League average is 7%.

02
Opportunity

Deep middle is open

49ers are worst against deep middle throws, allowing +1.29 EPA per attempt. Colts send 4% of their throws there. That is a small part of their offense so far.

03
Watch out

Checkdowns go nowhere

49ers give up 35 yards a game to running backs (23rd), against a league average of 32. Colts' running backs produce 29 (18th).

04
Wash

Yards per play

Call this one even. Colts gain 5.9 yards per play (8th). 49ers give up 5.6 (21st), with the league at 5.4.

The series · 49ers and Colts since 1999, and this season's records7 meetings

The Colts lead the series 5–2 since 1999 (they first met in 2001). This game is the latest meeting.

49ers at home0–3the 49ers' record
In Indianapolis2–2the 49ers' record
Most points49ers 48 · Colts 302025 · 2021
Biggest win49ers by 21 · Colts by 252025 · 2005

The last 5

2025 · Wk 16SF 48 at IND 27
2021 · Wk 7IND 30 at SF 18
2017 · Wk 5 · OTSF 23 at IND 26
2013 · Wk 3IND 27 at SF 7
2009 · Wk 8SF 14 at IND 18

2025 records

49ersColts
Overall12–58–9
Division4–22–4
Conference9–36–6
Other conference3–22–3
Home5–36–3
Away7–22–6
Last 5WWWWLLLLLL
StreakLost 1Lost 7
Points a game25.7 – 21.827.4 – 24.2

Every meeting since 1999, regular season and playoffs, from nflverse's game list, which starts in 1999; the all-time series goes back further. Franchises that moved count as one team (the Raiders, Chargers and Rams). Home and away are from the 49ers' side. Records are this regular season.

Head to head · IND offense against SF defense
StatIND IND offFavors IND · Favors SFSF SF def allowsNFL avg
Overall
EPA per play
+0.08#7
+0.07#24+0.01
Success rate
46%#6
49%#3044%
Yards per play
5.9#8
5.6#215.4
Explosive play rate
9%#19
8%#410%
Passing
Pass EPA per dropback
+0.06#10
+0.11#25+0.01
Sack rate
5%#7
4%#327%
Running
Run EPA per carry
+0.06#2
-0.02#23-0.05
Yards per carry
4.6#8
4.4#224.3
Money downs
3rd down conversion
43%#7
41%#1840%
Red zone TD rate
68%#3
59%#2059%
Targets by position
WR yards per game
154#11
144#19140
TE yards per game
57#10
53#1753
TE targets per game
8.2#9
8.1#237.3
RB receiving yards per game
29#18
35#2332
Where the ball goes · EPA per throwDeep is 15+ air yds

Colts: EPA per throw

Left
Middle
Right
Deep
+0.528% of throws
+1.234% of throws
+0.266% of throws
Short
+0.0133% of throws
+0.0816% of throws
+0.1632% of throws

49ers: EPA allowed per throw

Left
Middle
Right
Deep
+0.5158 throws
+1.2922 throws
+0.2649 throws
Short
+0.16200 throws
+0.15102 throws
-0.02201 throws

Green gains more than expected, red loses value. Cells with fewer than 5 throws are grayed out.