DOWN X DOWN › week 16 › 49ers at Chiefs
Updated Nov 3, 9:16 AM ET
2026
2026this season2025final

Week 16 · Sunday 4:25 PM ET · GEHA Field at Arrowhead Stadium

KCvsSF

Chiefs offensevs49ers defense

Season numbers through Week 8: 7 games for Chiefs, 7 for 49ers. Ranks are out of 32; #1 is the best offense or the stingiest defense.

SF offenseKC offense
Keys to the game · where this matchup tilts, from the season numbers4 reads
01
Biggest edge

Backs catch passes

49ers give up 49 yards a game to running backs (32nd), against a league average of 32. Chiefs' running backs produce 53 (1st).

02
Opportunity

Short left is open

49ers are worst against short left throws, allowing +0.36 EPA per attempt. Chiefs send 26% of their throws there.

03
Watch out

Wideouts get blanketed

49ers give up 132 yards a game to wide receivers (11th), against a league average of 147. Chiefs' wide receivers produce 118 (28th).

04
Wash

Yards per play

Call this one even. Chiefs gain 6.4 yards per play (3rd). 49ers give up 4.8 (4th), with the league at 5.4.

Players to watch

SF 49ers

13Brock PurdyQB · 146/211 · 1748 yds · 15 TD · 4 INTEPA per dropback +0.29 · 2nd23Christian McCaffreyRB · 84 car · 389 yds · 8 TD · 34 recEPA per touch +0.11 · 7th85George KittleTE · 34 rec · 425 yds · 5 TD · 46 tgtEPA per target +0.35 · 13th5Mike EvansWR · 27 rec · 420 yds · 3 TD · 39 tgtEPA per target +1.05 · 2nd0Renardo GreenLeft Cornerback · 26 tackles · 3 INT · 5 PD3 INT · T-2nd in the NFL99DeForest BucknerRight Defensive Tackle · 31 tackles · 4 sacks · 3 PD4 sacks · T-23rd in the NFL

KC Chiefs

15Patrick MahomesQB · 154/232 · 1795 yds · 12 TD · 4 INTEPA per dropback +0.14 · 14th9Kenneth Walker IIIRB · 141 car · 770 yds · 8 TD · 22 recEPA per touch +0.05 · 14th87Travis KelceTE · 29 rec · 410 yds · 2 TD · 42 tgtEPA per target +0.52 · 7th1Xavier WorthyWR · 27 rec · 230 yds · 1 TD · 41 tgtEPA per target -0.0656George KarlaftisLeft Defensive End · 24 tackles · 2 sacks · 1 INT · 8 PD2 sacks20Nohl WilliamsLeft Cornerback · 32 tackles · 1 sack · 1 INT · 7 PD1 INT
The series · 49ers and Chiefs since 1999, and this season's records10 meetings

The Chiefs lead the series 7–3 since 1999 (they first met in 2000). They have won the last 5. Oct 20, 2024, at Levi's Stadium: the Chiefs won 28–18. Brock Purdy started at quarterback for the 49ers and Patrick Mahomes for the Chiefs; Kyle Shanahan and Andy Reid coached.

49ers at home3–2the 49ers' record
In Kansas City0–3the 49ers' record
Most points49ers 27 · Chiefs 442018 · 2022
Biggest win49ers by 14 · Chiefs by 412000 · 2006
Playoffs0–2the 49ers' record

The last 5

2024 · Wk 7KC 28 at SF 18
2023 · Wk 22 · OT · playoffsSF 22 at KC 25
2022 · Wk 7KC 44 at SF 23
2019 · Wk 21 · playoffsSF 20 at KC 31
2018 · Wk 3SF 27 at KC 38

2026 records

49ersChiefs
Overall6–15–2
Division3–03–1
Conference4–15–1
Other conference2–00–1
Home4–03–0
Away2–12–2
Last 5WWWWLWWWLL
StreakLost 1Lost 2
Points a game28.1 – 19.923.9 – 18.7

Every meeting since 1999, regular season and playoffs, from nflverse's game list, which starts in 1999; the all-time series goes back further. Franchises that moved count as one team (the Raiders, Chargers and Rams). Home and away are from the 49ers' side. Records are this regular season.

The lineups · Chiefs offense against the 49ers defenseDepth charts
49ers defense · 4-3 DChiefs offense · 3WR 1TE70Benson66Caliendo52Humphrey65Smith77Moore87Kelce15Mahomes9Walker4Rice13Allen1Worthy97Bosa99Buckner92Odighizuwa56White57Greenlaw54Warner53Dugger2Lenoir0Green20Stout36Sigle27Brown

Chiefs offense · 3WR 1TE

  • QBPatrick Mahomes#15 · 154/232 · 1795 yds · 12 TD · 4 INT
  • RBKenneth Walker III#9 · 141 car · 770 yds · 8 TD · 22 rec
  • WRRashee Rice#4 · 20 rec · 243 yds · 2 TD · 25 tgt
  • WRXavier Worthy#1 · 27 rec · 230 yds · 1 TD · 41 tgt
  • WRCyrus Allen#13 · 5 rec · 65 yds · 0 TD · 9 tgt
  • TETravis Kelce#87 · 29 rec · 410 yds · 2 TD · 42 tgt
  • LTKahlil Benson#70
  • LGMike Caliendo#66
  • CCreed Humphrey#52
  • RGTrey Smith#65
  • RTJaylon Moore#77

49ers defense · Base 4-3 D

  • RDENick Bosa#97 · 7 tackles
  • RDTDeForest Buckner#99 · 31 tackles · 4 sacks · 3 PD
  • LDTOsa Odighizuwa#92 · 13 tackles · 2 sacks · 1 PD
  • LDEKeion White#56 · 13 tackles · 3.5 sacks
  • WLBDre Greenlaw#57 · 49 tackles
  • MLBFred Warner#54 · 70 tackles · 0.5 sacks · 3 PD
  • SLBJaden Dugger#53 · 30 tackles · 1 sack
  • RCBDeommodore Lenoir#2 · 30 tackles · 1 PD
  • LCBRenardo Green#0 · 26 tackles · 3 INT · 5 PD
  • NBUpton Stout#20 · 18 tackles · 0.5 sacks · 1 PD
  • SSMarques Sigle#36 · 26 tackles · 1 sack
  • FSJi'Ayir Brown#27 · 44 tackles · 2 PD

Starters from each team's current depth chart (nflverse, from ESPN), drawn in the offense's base three-receiver set against the defense's base front. The nickel back, the extra defensive back most teams use against three receivers, is drawn lighter. Left and right are as the offense sees the field. The toggle at the top flips which offense is drawn.

Head to head · KC offense against SF defense
StatKC KC offFavors KC · Favors SFSF SF def allowsNFL avg
Overall
EPA per play
+0.13#4
-0.05#8+0.00
Success rate
48%#6
44%#2044%
Yards per play
6.4#3
4.8#45.4
Explosive play rate
10%#9
4%#19%
Passing
Pass EPA per dropback
+0.14#9
+0.04#18+0.03
Sack rate
4%#4
6%#227%
Running
Run EPA per carry
+0.09#2
-0.18#2-0.08
Yards per carry
5.3#1
3.6#74.1
Money downs
3rd down conversion
40%#13
38%#1141%
Red zone TD rate
58%#19
48%#761%
Targets by position
WR yards per game
118#28
132#11147
TE yards per game
85#3
44#755
TE targets per game
8.7#7
7.9#197.6
RB receiving yards per game
53#1
49#3232
Where the ball goes · EPA per throwDeep is 15+ air yds

Chiefs: EPA per throw

Left
Middle
Right
Deep
+0.893% of throws
-0.295% of throws
+0.566% of throws
Short
+0.3026% of throws
+0.3419% of throws
+0.0741% of throws

49ers: EPA allowed per throw

Left
Middle
Right
Deep
-0.0514 throws
+0.637 throws
+0.0823 throws
Short
+0.3685 throws
-0.2024 throws
-0.0391 throws

Green gains more than expected, red loses value. Cells with fewer than 5 throws are grayed out.